5. Anti-CD8 antibodies can inhibit or enhance peptide-MHC class I (pMHCI) multimer binding: this is paralleled by their effects on CTL activation and occurs in the absence of an interaction between pMHCI and CD8 on the cell surface

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Wooldridge, L., Hutchinson, S. L., Choi, E. M., Lissina, A., Jones, E., Mirza, F., Dunbar, P. R., Price, D. A., Cerundolo, V., and Sewell, A. K. 2003. Anti-CD8 antibodies can inhibit or enhance peptide-MHC class I (pMHCI) multimer binding: this is paralleled by their effects on CTL activation and occurs in the absence of an interaction between pMHCI and CD8 on the cell surface. J Immunol 171:6650-6660. IF: 5.745.

**First paper to describe the pMHCI/CD8 independent effects of anti-CD8 antibodies. Cited 29 times.

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