22. MHC class I molecules with Superenhanced CD8 binding properties bypass the requirement for cognate TCR recognition and nonspecifically activate CTLs

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Wooldridge, L., M. Clement, A. Lissina, E. S. Edwards, K. Ladell, J. Ekeruche, R. E. Hewitt, B. Laugel, E. Gostick, D. K. Cole, R. Debets, C. Berrevoets, J. J. Miles, S. R. Burrows, D. A. Price, and A. K. Sewell. 2010. MHC class I molecules with Superenhanced CD8 binding properties bypass the requirement for cognate TCR recognition and nonspecifically activate CTLs. J Immunol 184:3357-3366. IF: 5.745.

**First paper to establish the biological significance of the low solution binding affinity of the pMHCI/CD8 interaction.

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